The patent of the Keytruda drug manufactured by Merck & Co. is estimated to expire in 2028, which has a reported peak annual sales of about ** billion U.S. dollars. The Eliquis drug, which is estimated to expire between 2026 and 2028, reported annual peak sales of about ** billion U.S. dollars.
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DrugPatentWatch. (February 15, 2026). Major drugs losing patent protection worldwide from 2025 to 2030 (in billion U.S. dollars) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 31, 2026, from /statistics/1660217/major-drugs-losing-patent-protection-globally/
DrugPatentWatch. "Major drugs losing patent protection worldwide from 2025 to 2030 (in billion U.S. dollars)." Chart. February 15, 2026. ÌÇÐÄÆƽâ°æ. Accessed July 31, 2026. /statistics/1660217/major-drugs-losing-patent-protection-globally/
DrugPatentWatch. (2026). Major drugs losing patent protection worldwide from 2025 to 2030 (in billion U.S. dollars). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 31, 2026. /statistics/1660217/major-drugs-losing-patent-protection-globally/
DrugPatentWatch. "Major Drugs Losing Patent Protection Worldwide from 2025 to 2030 (in Billion U.S. Dollars)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 15 Feb 2026, /statistics/1660217/major-drugs-losing-patent-protection-globally/
DrugPatentWatch, Major drugs losing patent protection worldwide from 2025 to 2030 (in billion U.S. dollars) ÌÇÐÄÆƽâ°æ, /statistics/1660217/major-drugs-losing-patent-protection-globally/ (last visited July 31, 2026)
Major drugs losing patent protection worldwide from 2025 to 2030 (in billion U.S. dollars) [Graph], DrugPatentWatch, February 15, 2026. [Online]. Available: /statistics/1660217/major-drugs-losing-patent-protection-globally/
