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In the United States, the net spending on medicines reached approximately *** billion U.S. dollars in 2025. The spending on medicine in the United States is likely to increase to *** billion U.S. dollars by 2030. 

How are drugs categorized in the United States?

Sales of brand-name drugs accounted for nearly an ** percent share of the money spent on medicines in the United States in 2023. Keytruda was the medicine that generated the most sales revenue in 2025, making about ** billion U.S. dollars per year. Drugs can be categorized in various ways, but one common method is to group them by therapeutic use, i.e., by the type of condition they are used to treat. Oncology drugs continue to be one of the categories where the most money is spent in the United States.

What is Humira used for?

Humira is a drug used to reduce the signs and symptoms of several autoimmune diseases in adults, such as rheumatoid arthritis. The drug, manufactured by the company AbbVie, was the leading pharmaceutical product worldwide based on sales before the COVID-19 vaccines entered the market. Sales of Humira account for a disproportionately large chunk of AbbVie’s total revenue. The prescription drug is given by an injection under the skin, and two kits of the Humira Pen (40 mg) cost an average of 6,209 U.S. dollars in the United States in 2022, which was far more expensive than in other selected countries.