U.S. top pharmacy online stores by net sales 2025| ��ƽ��

Top online stores in the pharmacy segment in the United States in 2025, by e-commerce net sales (in million U.S. dollar)

Characteristic	E-commerce revenue in million U.S. dollar
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Supplementary notes

Shops in the Pharmacies specialist group sell the classic product line of a pharmacy. That includes drugs with prescription and without (Over the counter drugs, OTC). Shops that focus on products like homeopathy and nutrition do not belong to this peer group.

The encompasses the sale of physical goods via a digital channel to a private end user (B2C). Incorporated in this definition are purchases via desktop computer (including notebooks and laptops) as well as purchases via mobile devices such as smartphones and tablets.

The following are not included in the e-commerce market: marketplace platforms only, digitally distributed services (e.g. travel tickets), online stores dedicated to digital media downloads or streams as well as online stores dedicated to B2B markets nor sales between private persons (C2C). Market volume, market growth and all monetary figures at store level refer to the annual e-commerce net sales after the deduction of returns.

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Citation formats

Walgreens.com is the online shop with the highest e-commerce net sales merchandising in pharmacy products in the U.S., with a revenue of *** billion U.S. dollars in 2025. CVS.com ranked second with *** billion dollars, and Nurx.com ranked third with **million dollars. That year, Walgreens.com was also the largest online pharmacy worldwide.

For an extended ranking or rankings in other product categories, please visit .