Note: The exact drug category is "Synthetic Opioids other than Methadone (primarily fentanyl) ICD-10 code (T40.4)". This category is dominated by fentanyl-related overdoses.
Citation formats
Number of fentanyl overdose deaths U.S. 1999-2023, by gender
In 2023, there were over 72,700 estimated overdose deaths in the U.S. primarily involving fentanyl. The majority involved males, with over 53,300 deaths, representing over 73 percent of all deceases.
Profit from the additional features of your individual account
Currently, you are using a shared account. To use individual functions (e.g., mark statistics as favourites, set
statistic alerts) please log in with your personal account.
If you are an admin, please authenticate by logging in again.
Learn more about how ÌÇÐÄÆƽâ°æ can support your business.
NIDA. (January 16, 2025). Number of overdose deaths from fentanyl in the U.S. from 1999 to 2023, by gender [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 22, 2026, from /statistics/895954/fentanyl-overdose-deaths-us-by-gender/
NIDA. "Number of overdose deaths from fentanyl in the U.S. from 1999 to 2023, by gender." Chart. January 16, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 22, 2026. /statistics/895954/fentanyl-overdose-deaths-us-by-gender/
NIDA. (2025). Number of overdose deaths from fentanyl in the U.S. from 1999 to 2023, by gender. ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 22, 2026. /statistics/895954/fentanyl-overdose-deaths-us-by-gender/
NIDA. "Number of Overdose Deaths from Fentanyl in The U.S. from 1999 to 2023, by Gender." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 16 Jan 2025, /statistics/895954/fentanyl-overdose-deaths-us-by-gender/
NIDA, Number of overdose deaths from fentanyl in the U.S. from 1999 to 2023, by gender ÌÇÐÄÆƽâ°æ, /statistics/895954/fentanyl-overdose-deaths-us-by-gender/ (last visited July 22, 2026)
Number of overdose deaths from fentanyl in the U.S. from 1999 to 2023, by gender [Graph], NIDA, January 16, 2025. [Online]. Available: /statistics/895954/fentanyl-overdose-deaths-us-by-gender/
