The official category is "Synthetic Opioids other than Methadone (primarily fentanyl) ICD-10 code (T40.4)" However, this category is dominated by fentanyl related overdoses.
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Rate of overdose deaths involving fentanyl in the U.S. 1999-2023
In 2023, there were around 22 overdose deaths in the United States involving fentanyl per 100,000 people. This is the first time that the overdose death rate has shown a decrease since 2010.
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NIDA. (January 16, 2025). Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023 (per 100,000 population) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 19, 2026, from /statistics/1018679/fentanyl-overdose-death-rate-us/
NIDA. "Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023 (per 100,000 population)." Chart. January 16, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 19, 2026. /statistics/1018679/fentanyl-overdose-death-rate-us/
NIDA. (2025). Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023 (per 100,000 population). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 19, 2026. /statistics/1018679/fentanyl-overdose-death-rate-us/
NIDA. "Rate of Drug Overdose Deaths Involving Fentanyl in The U.S. from 1999 to 2023 (per 100,000 Population)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 16 Jan 2025, /statistics/1018679/fentanyl-overdose-death-rate-us/
NIDA, Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023 (per 100,000 population) ÌÇÐÄÆƽâ°æ, /statistics/1018679/fentanyl-overdose-death-rate-us/ (last visited July 19, 2026)
Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2023 (per 100,000 population) [Graph], NIDA, January 16, 2025. [Online]. Available: /statistics/1018679/fentanyl-overdose-death-rate-us/
