* Other Synthetic Narcotics (other than methadone) ICD-10 code (T40.4) This category is dominated by fentanyl related overdoses.
** Prescription Opioids ICD-10 codes (T40.2-T40.3).
Citation formats
Deaths from drug overdose in the U.S. 2021-2023, by drug
In 2023, overdose deaths involving opioids in the United States totaled over *. The majority of opioid deaths involved fentanyl. The majority of death overdoses caused by fentanyl occur to males.
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NIDA. (January 16, 2025). Number of drug overdose deaths in the U.S. from 2021 to 2023, by drug [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 22, 2026, from /statistics/634084/drug-overdose-deaths-us-by-type/
NIDA. "Number of drug overdose deaths in the U.S. from 2021 to 2023, by drug ." Chart. January 16, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 22, 2026. /statistics/634084/drug-overdose-deaths-us-by-type/
NIDA. (2025). Number of drug overdose deaths in the U.S. from 2021 to 2023, by drug . ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 22, 2026. /statistics/634084/drug-overdose-deaths-us-by-type/
NIDA. "Number of Drug Overdose Deaths in The U.S. from 2021 to 2023, by Drug ." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 16 Jan 2025, /statistics/634084/drug-overdose-deaths-us-by-type/
NIDA, Number of drug overdose deaths in the U.S. from 2021 to 2023, by drug ÌÇÐÄÆƽâ°æ, /statistics/634084/drug-overdose-deaths-us-by-type/ (last visited July 22, 2026)
Number of drug overdose deaths in the U.S. from 2021 to 2023, by drug [Graph], NIDA, January 16, 2025. [Online]. Available: /statistics/634084/drug-overdose-deaths-us-by-type/
