Prescription opioid death rate by gender U.S. 1999-2023

U.S. death rate from prescription opioid overdose from 1999 to 2023, by gender (per 100,000 population)

Death rate due to prescription opioid overdose U.S. 1999-2023, by gender

Last update:

Nov 18, 2025

Author:

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Regions:

North America, United States

Survey time period:

From 01/01/1999 to 31/12/2023

In 2023, males in the United States had a prescription opioid overdose death rate of per 100,000 population. This figure reached almost deaths per 100,000 in women. Overall, the death rate due to prescription opioids in the North American country has fluctuated, but also increased since 1999.

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U.S. death rate from prescription opioid overdose from 1999 to 2023, by gender (per 100,000 population)

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