In 2004, levothyroxine was prescribed over 87 million times. Two decades later, the number of prescriptions for this drug stood at around 81 million. Levothyroxine is primarily used for the treatment of thyroid hormone deficiency. This statistic shows the total annual number of levothyroxine prescriptions in the U.S. from 2004 to 2023, in millions.
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ClinCalc. (August 10, 2025). Number of levothyroxine prescriptions in the U.S. from 2004 to 2023 (in millions) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 28, 2026, from /statistics/780284/levothyroxine-prescriptions-number-in-the-us/
ClinCalc. "Number of levothyroxine prescriptions in the U.S. from 2004 to 2023 (in millions)." Chart. August 10, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 28, 2026. /statistics/780284/levothyroxine-prescriptions-number-in-the-us/
ClinCalc. (2025). Number of levothyroxine prescriptions in the U.S. from 2004 to 2023 (in millions). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 28, 2026. /statistics/780284/levothyroxine-prescriptions-number-in-the-us/
ClinCalc. "Number of Levothyroxine Prescriptions in The U.S. from 2004 to 2023 (in Millions)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 10 Aug 2025, /statistics/780284/levothyroxine-prescriptions-number-in-the-us/
ClinCalc, Number of levothyroxine prescriptions in the U.S. from 2004 to 2023 (in millions) ÌÇÐÄÆƽâ°æ, /statistics/780284/levothyroxine-prescriptions-number-in-the-us/ (last visited July 28, 2026)
Number of levothyroxine prescriptions in the U.S. from 2004 to 2023 (in millions) [Graph], ClinCalc, August 10, 2025. [Online]. Available: /statistics/780284/levothyroxine-prescriptions-number-in-the-us/
