Total number of studies registered on ClinicalTrials.gov since 2000, based on the First Received date. Numbers are as of end of each year. The first version of ClinicalTrials.gov was made available to the public on February 29, 2000.
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Total number of registered clinical studies worldwide 2000-2025
Clinical studies play a crucial role in the global drug development process. The number of registered clinical trials has increased significantly in recent years. In 2025, there were over **clinical studies registered globally. The number of clinical studies has increased significantly since there were just registered in 2000. In general, clinical trials have grown more complex in recent years and remain vital for the research and development of new drugs and products.
Research and development
Research and development are an essential part of pharmaceutical companies and include drug development and product development. Among all industry sectors, the pharmaceutical industry spends the largest percentage of its revenue on research and development. Many companies are active in pharmaceutical research and development globally. It is projected that Swiss company Roche will remain one of the largest research and development spenders among pharmaceutical companies in the near future.
Clinical studies globally
Most clinical studies occurring globally are held in countries outside the U.S. Many clinical trials performed outside the U.S. and EU are done so because it is often easier and cheaper to conduct trials in other locations. Success rates for clinical trials depend heavily on the stage of the trial and the drugs or products being developed. Recent data suggested that only around ** percent of drugs make it from phase II to phase III.
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ClinicalTrials.gov. (January 21, 2026). Total number of registered clinical studies worldwide from 2000 to 2025 [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 27, 2026, from /statistics/732997/number-of-registered-clinical-studies-worldwide/
ClinicalTrials.gov. "Total number of registered clinical studies worldwide from 2000 to 2025." Chart. January 21, 2026. ÌÇÐÄÆÆ½â°æ. Accessed July 27, 2026. /statistics/732997/number-of-registered-clinical-studies-worldwide/
ClinicalTrials.gov. (2026). Total number of registered clinical studies worldwide from 2000 to 2025. ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 27, 2026. /statistics/732997/number-of-registered-clinical-studies-worldwide/
ClinicalTrials.gov. "Total Number of Registered Clinical Studies Worldwide from 2000 to 2025." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 21 Jan 2026, /statistics/732997/number-of-registered-clinical-studies-worldwide/
ClinicalTrials.gov, Total number of registered clinical studies worldwide from 2000 to 2025 ÌÇÐÄÆÆ½â°æ, /statistics/732997/number-of-registered-clinical-studies-worldwide/ (last visited July 27, 2026)
Total number of registered clinical studies worldwide from 2000 to 2025 [Graph], ClinicalTrials.gov, January 21, 2026. [Online]. Available: /statistics/732997/number-of-registered-clinical-studies-worldwide/