In 2004, acetaminophen was prescribed over six million times. In 2023, the number of acetaminophen prescriptions was, again, at around six million. Acetaminophen is primarily used to treat pain and fever. This statistic shows the total annual number of acetaminophen prescriptions in the U.S. from 2004 to 2023, in millions.
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ClinCalc. (August 10, 2025). Number of acetaminophen prescriptions in the U.S. from 2004 to 2023 (in millions) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 21, 2026, from /statistics/781739/acetaminophen-prescriptions-number-in-the-us/
ClinCalc. "Number of acetaminophen prescriptions in the U.S. from 2004 to 2023 (in millions)." Chart. August 10, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 21, 2026. /statistics/781739/acetaminophen-prescriptions-number-in-the-us/
ClinCalc. (2025). Number of acetaminophen prescriptions in the U.S. from 2004 to 2023 (in millions). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 21, 2026. /statistics/781739/acetaminophen-prescriptions-number-in-the-us/
ClinCalc. "Number of Acetaminophen Prescriptions in The U.S. from 2004 to 2023 (in Millions)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 10 Aug 2025, /statistics/781739/acetaminophen-prescriptions-number-in-the-us/
ClinCalc, Number of acetaminophen prescriptions in the U.S. from 2004 to 2023 (in millions) ÌÇÐÄÆƽâ°æ, /statistics/781739/acetaminophen-prescriptions-number-in-the-us/ (last visited July 21, 2026)
Number of acetaminophen prescriptions in the U.S. from 2004 to 2023 (in millions) [Graph], ClinCalc, August 10, 2025. [Online]. Available: /statistics/781739/acetaminophen-prescriptions-number-in-the-us/
