This statistic depicts the total number of e-prescriptions for controlled substances (like opioids) in the United States, based on data of the country's largest e-prescribing operator Surescripts, from 2013 to 2024. In 2024, the total number of filed electronic prescriptions for controlled substances exceeded 310 million.
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Surescripts. (March 24, 2025). Number of e-prescriptions for controlled substances in the United States from 2013 to 2024 (in millions) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 24, 2026, from /statistics/864367/number-of-us-e-prescriptions-for-controlled-substances/
Surescripts. "Number of e-prescriptions for controlled substances in the United States from 2013 to 2024 (in millions)." Chart. March 24, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 24, 2026. /statistics/864367/number-of-us-e-prescriptions-for-controlled-substances/
Surescripts. (2025). Number of e-prescriptions for controlled substances in the United States from 2013 to 2024 (in millions). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 24, 2026. /statistics/864367/number-of-us-e-prescriptions-for-controlled-substances/
Surescripts. "Number of E-prescriptions for Controlled Substances in The United States from 2013 to 2024 (in Millions)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 24 Mar 2025, /statistics/864367/number-of-us-e-prescriptions-for-controlled-substances/
Surescripts, Number of e-prescriptions for controlled substances in the United States from 2013 to 2024 (in millions) ÌÇÐÄÆƽâ°æ, /statistics/864367/number-of-us-e-prescriptions-for-controlled-substances/ (last visited July 24, 2026)
Number of e-prescriptions for controlled substances in the United States from 2013 to 2024 (in millions) [Graph], Surescripts, March 24, 2025. [Online]. Available: /statistics/864367/number-of-us-e-prescriptions-for-controlled-substances/
