"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third-party payer (e.g., Medicare or private insurance) and does not represent the total drug cost.
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Insulin human combination out-of-pocket price in the U.S. 2014-2023
In 2023, combinations of insulin human/insulin isophane human cost about ** U.S. dollars on average, compared to about ** U.S. dollars in 2021. This statistic shows the average out-of-pocket cost of combined insulin human and insulin isophane human in the U.S. from 2014 to 2023, in U.S. dollars.
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ClinCalc. (August 10, 2025). Insulin human/insulin isophane human out-of-pocket cost in the U.S. from 2014 to 2023 (in U.S. dollars) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 29, 2026, from /statistics/825337/insulin-human-out-of-pocket-cost-us/
ClinCalc. "Insulin human/insulin isophane human out-of-pocket cost in the U.S. from 2014 to 2023 (in U.S. dollars)." Chart. August 10, 2025. ÌÇÐÄÆƽâ°æ. Accessed July 29, 2026. /statistics/825337/insulin-human-out-of-pocket-cost-us/
ClinCalc. (2025). Insulin human/insulin isophane human out-of-pocket cost in the U.S. from 2014 to 2023 (in U.S. dollars). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 29, 2026. /statistics/825337/insulin-human-out-of-pocket-cost-us/
ClinCalc. "Insulin Human/Insulin Isophane Human Out-of-pocket Cost in The U.S. from 2014 to 2023 (in U.S. Dollars)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 10 Aug 2025, /statistics/825337/insulin-human-out-of-pocket-cost-us/
ClinCalc, Insulin human/insulin isophane human out-of-pocket cost in the U.S. from 2014 to 2023 (in U.S. dollars) ÌÇÐÄÆƽâ°æ, /statistics/825337/insulin-human-out-of-pocket-cost-us/ (last visited July 29, 2026)
Insulin human/insulin isophane human out-of-pocket cost in the U.S. from 2014 to 2023 (in U.S. dollars) [Graph], ClinCalc, August 10, 2025. [Online]. Available: /statistics/825337/insulin-human-out-of-pocket-cost-us/
