In 2025, CVS Health Corporation was the leading drugstore in the United States, recording about * billion U.S. dollars in retail sales. Second in the ranking came Walgreens Boots Alliance, with around * billion U.S. dollars.Â
The leading drugstore in the U.S.
The global brand value of CVS added up to over 30 billion U.S. dollars in 2024. In 2023, the company generated about billion U.S. dollars from its pharmacy retail segment, and in the same year, it was the leading U.S. drugstore with the highest number of physical stores in the country.
Walgreens Boots Alliance
Walgreens Boots Alliance is not only a leading health and beauty destination for consumers in the United States, but it also boasts an international presence. Despite generating most of its total sales in the U.S. region, the company recorded an increase in sales also in the United Kingdom and in Germany as of 2024. In 2023, the number of Boots stores in the UK added up to about , only slightly lower than in the previous financial year.
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National Retail Federation. (July 1, 2026). Leading drugstores in the United States in 2025, based on retail sales (in billion U.S. dollars) [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved August 03, 2026, from /statistics/197850/2010-sales-of-drug-stores-in-the-us/
National Retail Federation. "Leading drugstores in the United States in 2025, based on retail sales (in billion U.S. dollars)." Chart. July 1, 2026. ÌÇÐÄÆÆ½â°æ. Accessed August 03, 2026. /statistics/197850/2010-sales-of-drug-stores-in-the-us/
National Retail Federation. (2026). Leading drugstores in the United States in 2025, based on retail sales (in billion U.S. dollars). ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: August 03, 2026. /statistics/197850/2010-sales-of-drug-stores-in-the-us/
National Retail Federation. "Leading Drugstores in The United States in 2025, Based on Retail Sales (in Billion U.S. Dollars)." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 1 Jul 2026, /statistics/197850/2010-sales-of-drug-stores-in-the-us/
National Retail Federation, Leading drugstores in the United States in 2025, based on retail sales (in billion U.S. dollars) ÌÇÐÄÆÆ½â°æ, /statistics/197850/2010-sales-of-drug-stores-in-the-us/ (last visited August 03, 2026)
Leading drugstores in the United States in 2025, based on retail sales (in billion U.S. dollars) [Graph], National Retail Federation, July 1, 2026. [Online]. Available: /statistics/197850/2010-sales-of-drug-stores-in-the-us/