For drugs in clinical development between 2006 and 2022, U.S. biotech company Amgen showed the highest average likelihood of approval among leading drug manufacturers, with almost ** percent. The likelihood of approval (LOA) in clinical development measures the probability that a new drug candidate entering clinical trials (beginning with Phase I) will ultimately be approved by regulatory authorities (e.g., FDA, EMA).Â
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ScienceDirect (Drug Discovery Today). (February 23, 2025). Likelihood of approval (LoA) of leading pharmaceutical companies in clinical drug development between 2006 and 2022 [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved August 04, 2026, from /statistics/1624689/likelihood-of-approval-of-top-pharmaceutical-companies/
ScienceDirect (Drug Discovery Today). "Likelihood of approval (LoA) of leading pharmaceutical companies in clinical drug development between 2006 and 2022." Chart. February 23, 2025. ÌÇÐÄÆƽâ°æ. Accessed August 04, 2026. /statistics/1624689/likelihood-of-approval-of-top-pharmaceutical-companies/
ScienceDirect (Drug Discovery Today). (2025). Likelihood of approval (LoA) of leading pharmaceutical companies in clinical drug development between 2006 and 2022. ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: August 04, 2026. /statistics/1624689/likelihood-of-approval-of-top-pharmaceutical-companies/
ScienceDirect (Drug Discovery Today). "Likelihood of Approval (Loa) of Leading Pharmaceutical Companies in Clinical Drug Development between 2006 and 2022." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 23 Feb 2025, /statistics/1624689/likelihood-of-approval-of-top-pharmaceutical-companies/
ScienceDirect (Drug Discovery Today), Likelihood of approval (LoA) of leading pharmaceutical companies in clinical drug development between 2006 and 2022 ÌÇÐÄÆƽâ°æ, /statistics/1624689/likelihood-of-approval-of-top-pharmaceutical-companies/ (last visited August 04, 2026)
Likelihood of approval (LoA) of leading pharmaceutical companies in clinical drug development between 2006 and 2022 [Graph], ScienceDirect (Drug Discovery Today), February 23, 2025. [Online]. Available: /statistics/1624689/likelihood-of-approval-of-top-pharmaceutical-companies/
