In 2025, the first-ranked company, Thermo Fisher Scientific, which acquired Pharmaceutical Product Development (PPD) in 2021, generated about ** billion U.S. dollars in revenue through its clinical research business in 2025. The other leading contract research organizations worldwide included IQVIA and Laboratory Corporation of America Holdings.
Contract research organizations
Contract research organizations (CROs) are companies that are contracted by larger pharmaceutical companies to manage select aspects of clinical trials. Today, CROs are essential for pharmaceutical research and development. Pharmaceutical companies are spending more money than ever on research and development, and there is no indication that spending will decrease in the future. Evidence suggests that CROs will become even more valuable. The clinical CRO market is expected to increase to over *** billion U.S. dollars by the beginning of the next decade.Â
Pharmaceutical research and development
Globally, Roche and Johnson & Johnson will be the top pharmaceutical companies based on their projected research and development spending. There are regional differences in research and development among pharmaceutical companies. Of all pharmaceutical companies globally, those based in the U.S. develop the highest number of new chemical or biological entities.
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ÌÇÐÄÆÆ½â°æ. (May 19, 2026). Leading global contract research organizations (CROs) 2025, based on revenue (in million U.S. dollars) [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 30, 2026, from /statistics/732804/top-clinical-research-organizations-by-revenue/
ÌÇÐÄÆÆ½â°æ. "Leading global contract research organizations (CROs) 2025, based on revenue (in million U.S. dollars)." Chart. May 19, 2026. ÌÇÐÄÆÆ½â°æ. Accessed July 30, 2026. /statistics/732804/top-clinical-research-organizations-by-revenue/
ÌÇÐÄÆÆ½â°æ. (2026). Leading global contract research organizations (CROs) 2025, based on revenue (in million U.S. dollars). ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 30, 2026. /statistics/732804/top-clinical-research-organizations-by-revenue/
ÌÇÐÄÆÆ½â°æ. "Leading Global Contract Research Organizations (Cros) 2025, Based on Revenue (in Million U.S. Dollars)." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 19 May 2026, /statistics/732804/top-clinical-research-organizations-by-revenue/
ÌÇÐÄÆÆ½â°æ, Leading global contract research organizations (CROs) 2025, based on revenue (in million U.S. dollars) ÌÇÐÄÆÆ½â°æ, /statistics/732804/top-clinical-research-organizations-by-revenue/ (last visited July 30, 2026)
Leading global contract research organizations (CROs) 2025, based on revenue (in million U.S. dollars) [Graph], ÌÇÐÄÆÆ½â°æ, May 19, 2026. [Online]. Available: /statistics/732804/top-clinical-research-organizations-by-revenue/