In 2025, Merck & Co.’s Keytruda generated nearly ** billion U.S. dollars, making it the number one ranking cancer drug worldwide in terms of revenue. Other oncology products among the top ten included Revlimid, Opdivo, and Tagrisso.Â
Pharmaceutical outlook
Cancer drug Keytruda is already exceeding original projections in terms of revenue. Pharmaceutical sales numbers are forecast to be the highest in North America by 2028. It is predicted that sales numbers will reach around *** billion U.S. dollars in this region, which would be nearly three times the sales numbers expected from the runner-up, the European Union.Â
Cancer cases by gender
Specific types of cancer are more common among certain genders. Worldwide, breast cancer accounted for approximately a quarter of all new cancer cases among females of all ages in 2022. Lung cancer was the second most common type of cancer for women. For men, lung and prostate cancer were the most common types that year. Some ** percent of new male cases involved lung cancer, while about ** percent were prostate cancer cases.
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Drug Discovery & Development. (April 10, 2026). Leading cancer drugs worldwide by revenue in 2025 (in billion U.S. dollars) [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 28, 2026, from /statistics/288538/top-cancer-drugs-based-on-revenue/
Drug Discovery & Development. "Leading cancer drugs worldwide by revenue in 2025 (in billion U.S. dollars)." Chart. April 10, 2026. ÌÇÐÄÆÆ½â°æ. Accessed July 28, 2026. /statistics/288538/top-cancer-drugs-based-on-revenue/
Drug Discovery & Development. (2026). Leading cancer drugs worldwide by revenue in 2025 (in billion U.S. dollars). ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 28, 2026. /statistics/288538/top-cancer-drugs-based-on-revenue/
Drug Discovery & Development. "Leading Cancer Drugs Worldwide by Revenue in 2025 (in Billion U.S. Dollars)." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 10 Apr 2026, /statistics/288538/top-cancer-drugs-based-on-revenue/
Drug Discovery & Development, Leading cancer drugs worldwide by revenue in 2025 (in billion U.S. dollars) ÌÇÐÄÆÆ½â°æ, /statistics/288538/top-cancer-drugs-based-on-revenue/ (last visited July 28, 2026)
Leading cancer drugs worldwide by revenue in 2025 (in billion U.S. dollars) [Graph], Drug Discovery & Development, April 10, 2026. [Online]. Available: /statistics/288538/top-cancer-drugs-based-on-revenue/