This statistic represents the number of people who died from overdose and tested positive for xylazine by region in the United States in 2020 and 2021. The South of the United States had the highest number of deaths, with 1,423 xylazine-positive deaths in 2021.
Xylazine is a veterinary anesthetic that has been used in humans in the United States for several years. When mixed with fentanyl or other drugs or opioids, xylazine allows users to experience effects at a lower cost. It is notably used to produce the "zombie drug" or "tranq." Users are often recognized by their skin wounds.
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Drug Enforcement Administration. (October 17, 2022). Number of people who died from overdose and tested positive for xylazine by region in the United States in 2020 and 2021 [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 25, 2026, from /statistics/1648923/number-deaths-overdose-xylazine/
Drug Enforcement Administration. "Number of people who died from overdose and tested positive for xylazine by region in the United States in 2020 and 2021." Chart. October 17, 2022. ÌÇÐÄÆÆ½â°æ. Accessed July 25, 2026. /statistics/1648923/number-deaths-overdose-xylazine/
Drug Enforcement Administration. (2022). Number of people who died from overdose and tested positive for xylazine by region in the United States in 2020 and 2021. ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 25, 2026. /statistics/1648923/number-deaths-overdose-xylazine/
Drug Enforcement Administration. "Number of People Who Died from Overdose and Tested Positive for Xylazine by Region in The United States in 2020 and 2021." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 17 Oct 2022, /statistics/1648923/number-deaths-overdose-xylazine/
Drug Enforcement Administration, Number of people who died from overdose and tested positive for xylazine by region in the United States in 2020 and 2021 ÌÇÐÄÆÆ½â°æ, /statistics/1648923/number-deaths-overdose-xylazine/ (last visited July 25, 2026)
Number of people who died from overdose and tested positive for xylazine by region in the United States in 2020 and 2021 [Graph], Drug Enforcement Administration, October 17, 2022. [Online]. Available: /statistics/1648923/number-deaths-overdose-xylazine/