In 2019, the global age-standardized prevalence rate of Down syndrome was around 21.51 per 100,000 population. The prevalence rate of Down syndrome is slightly higher among males than females. This statistic shows the age-standardized prevalence rate of Down syndrome worldwide in 1990 and 2019, by gender.
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Frontiers (Frontiers in Genetics). (July 14, 2022). Prevalence rate of Down syndrome worldwide in 1990 and 2019, by gender (per 100,000 population) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 27, 2026, from /statistics/1498090/global-down-syndrome-prevalence-rate-by-gender/
Frontiers (Frontiers in Genetics). "Prevalence rate of Down syndrome worldwide in 1990 and 2019, by gender (per 100,000 population)." Chart. July 14, 2022. ÌÇÐÄÆƽâ°æ. Accessed July 27, 2026. /statistics/1498090/global-down-syndrome-prevalence-rate-by-gender/
Frontiers (Frontiers in Genetics). (2022). Prevalence rate of Down syndrome worldwide in 1990 and 2019, by gender (per 100,000 population). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 27, 2026. /statistics/1498090/global-down-syndrome-prevalence-rate-by-gender/
Frontiers (Frontiers in Genetics). "Prevalence Rate of Down Syndrome Worldwide in 1990 and 2019, by Gender (per 100,000 Population)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 14 Jul 2022, /statistics/1498090/global-down-syndrome-prevalence-rate-by-gender/
Frontiers (Frontiers in Genetics), Prevalence rate of Down syndrome worldwide in 1990 and 2019, by gender (per 100,000 population) ÌÇÐÄÆƽâ°æ, /statistics/1498090/global-down-syndrome-prevalence-rate-by-gender/ (last visited July 27, 2026)
Prevalence rate of Down syndrome worldwide in 1990 and 2019, by gender (per 100,000 population) [Graph], Frontiers (Frontiers in Genetics), July 14, 2022. [Online]. Available: /statistics/1498090/global-down-syndrome-prevalence-rate-by-gender/
