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Number of live births per one incidence of Down syndrome in the United States as of 2024, by maternal age

Age of mother	Number of live births per one incidence of Down syndrome
20 years	2,000
21 years	1,700
22 years	1,500
23 years	1,400
24 years	1,300
25 years	1,200
26 years	1,100
27 years	1,050
28 years	1,000
29 years	950
30 years	900
31 years	800
32 years	720
33 years	600
34 years	450
35 years	350
36 years	300
37 years	250
38 years	200
39 years	150
40 years	100
41 years	80
42 years	70
43 years	50
44 years	40
45 years	30
46 years	25
47 years	20
48 years	15
49 years	10

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Release date

October 2024

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Region

United States

Survey time period

as of 2024

Supplementary notes

Release date represents the date figures were accessed.

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Older women are at an increased risk of having a child with Down syndrome. For example, among women aged 20 years, the chances of conceiving a child with Down syndrome is about one in 2,000. In comparison, among women aged 49 years, the chances of conceiving a child with Down syndrome is about one in 10. This statistic shows the incidence of Down syndrome in the United States as of 2024, by maternal age.

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