In 2019, the global age-standardized death rate for Down syndrome was around 0.3 per 100,000 population. At that time, the death rate for Down syndrome was highest in Tropical Latin America, with around 0.7 deaths per 100,000 population. The most common cause of death for adults and children with Down syndrome is respiratory infection. This statistic shows the age-standardized death rate for Down syndrome worldwide in 1990 and 2019, by region.
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Frontiers (Frontiers in Genetics). (July 14, 2022). Death rate for Down syndrome worldwide in 1990 and 2019, by region (per 100,000 population) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 30, 2026, from /statistics/1498107/global-down-syndrome-death-rate-by-region/
Frontiers (Frontiers in Genetics). "Death rate for Down syndrome worldwide in 1990 and 2019, by region (per 100,000 population)." Chart. July 14, 2022. ÌÇÐÄÆƽâ°æ. Accessed July 30, 2026. /statistics/1498107/global-down-syndrome-death-rate-by-region/
Frontiers (Frontiers in Genetics). (2022). Death rate for Down syndrome worldwide in 1990 and 2019, by region (per 100,000 population). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 30, 2026. /statistics/1498107/global-down-syndrome-death-rate-by-region/
Frontiers (Frontiers in Genetics). "Death Rate for Down Syndrome Worldwide in 1990 and 2019, by Region (per 100,000 Population)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 14 Jul 2022, /statistics/1498107/global-down-syndrome-death-rate-by-region/
Frontiers (Frontiers in Genetics), Death rate for Down syndrome worldwide in 1990 and 2019, by region (per 100,000 population) ÌÇÐÄÆƽâ°æ, /statistics/1498107/global-down-syndrome-death-rate-by-region/ (last visited July 30, 2026)
Death rate for Down syndrome worldwide in 1990 and 2019, by region (per 100,000 population) [Graph], Frontiers (Frontiers in Genetics), July 14, 2022. [Online]. Available: /statistics/1498107/global-down-syndrome-death-rate-by-region/
