The source openly states that figures could be "overestimates" as individuals can use multiple unique addresses; The source does not state whether these transactions were measured on the Ethereum blockchain alone or on other blockchains as well.
Supplementary notes
Monthly figures are as of the beginning of that particular month.
Figures have been rounded.
Citation formats
Monthly number of unique DeFi users worldwide up to May 2026
Decentralized Finance users reached a peak of **** million unique users in 2025, although figures in 2025 are usually lower. This is according to a network crawling code that tries to measure the number of unique user addresses involved in buying or selling specific projects associated with DeFi. For example, the code lists data-fetching commands associated with Uniswap and Aave — two DeFi protocols with a market cap that was higher than one billion U.S. dollars in March 2022. As decentralized finance—much like cryptocurrencies or NFTs — are not being tracked by an official government, these procedures try to measure "network activity". Such activity on the Ethereum blockchain/network, the most used blockchain for DeFi, or elsewhere — tend to be the only source of information on the market size of these topics. However, the source does acknowledge the numbers shown are not without their potential flaws.
DeFi in 2025 is relatively small-scale
Often remarked as a potential breakthrough trend for 2024, the TVL (total value locked) of DeFi in 2025 reveals a market that is much smaller than in 2021. The amount of money stored in decentralized finance was worth about billion U.S. dollars by May 2025, compared to *** billion U.S. dollars at the end of 2021. Two reasons can be named for this decline. First, the overall cryptocurrency markets had witnessed several dramatic moments. Prices declined after the crash of stablecoin LUNA and the sudden collapse of crypto exchange FTX in 2022. In 2023, the United States government handed out one of its largest-ever corporate fines to Binance — the world's largest crypto exchange. Second, analysts believe the high yield on U.S. Treasury bonds in 2025 when compared to DeFi yields negatively impacted the young industry — as these bonds pose lower risk than DeFi.
DeFi use cases: Supporting crypto investments
Decentralized Finance hopes to offer different digital financial services, which are run by a community in a so-called decentralized autonomous organization (DAO) away from banks or governments. These services can include asset management, money lending, or trading, potentially making it possible to offer services that traditional finance cannot do. By May 2025, however, DeFi focused on two main use cases: Liquid staking and money lending. These processes are there to support crypto investors, specifically. The market size of insurance within decentralized finance, for example, was much smaller in comparison.
Profit from the additional features of your individual account
Currently, you are using a shared account. To use individual functions (e.g., mark statistics as favourites, set
statistic alerts) please log in with your personal account.
If you are an admin, please authenticate by logging in again.
Learn more about how ÌÇÐÄÆÆ½â°æ can support your business.
Dune Analytics, & ÌÇÐÄÆÆ½â°æ. (June 8, 2026). Number of unique addresses that either bought or sold a Decentralized Finance (DeFi) asset worldwide from November 2018 to May 2026 [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 16, 2026, from /statistics/1297745/defi-user-number/
Dune Analytics, und ÌÇÐÄÆÆ½â°æ. "Number of unique addresses that either bought or sold a Decentralized Finance (DeFi) asset worldwide from November 2018 to May 2026." Chart. June 8, 2026. ÌÇÐÄÆÆ½â°æ. Accessed July 16, 2026. /statistics/1297745/defi-user-number/
Dune Analytics, ÌÇÐÄÆÆ½â°æ. (2026). Number of unique addresses that either bought or sold a Decentralized Finance (DeFi) asset worldwide from November 2018 to May 2026. ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 16, 2026. /statistics/1297745/defi-user-number/
Dune Analytics, and ÌÇÐÄÆÆ½â°æ. "Number of Unique Addresses That Either Bought or Sold a Decentralized Finance (Defi) Asset Worldwide from November 2018 to May 2026." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 8 Jun 2026, /statistics/1297745/defi-user-number/
Dune Analytics & ÌÇÐÄÆÆ½â°æ, Number of unique addresses that either bought or sold a Decentralized Finance (DeFi) asset worldwide from November 2018 to May 2026 ÌÇÐÄÆÆ½â°æ, /statistics/1297745/defi-user-number/ (last visited July 16, 2026)
Number of unique addresses that either bought or sold a Decentralized Finance (DeFi) asset worldwide from November 2018 to May 2026 [Graph], Dune Analytics, & ÌÇÐÄÆÆ½â°æ, June 8, 2026. [Online]. Available: /statistics/1297745/defi-user-number/