Deaths are classified using the International Classification of Diseases, Tenth Revision (ICD–10). Drug overdose deaths are identified using underlying cause-of-death codes X40–X44, X60–X64, X85, and Y10–Y14. Age-adjusted death rates were calculated by applying age-specific death rates to the 2000 U.S standard population age distribution.
Figures for 1999 and 2000 were taken from the previous year's report and can .
Citation formats
U.S. drug overdose age-adjusted death rates 1999-2023
In 2023, the age-adjusted drug overdose death rate in the United States was **** per 100,000 population. Opioids are the main driver of overdose deaths in the United States. This statistic presents the age-adjusted drug overdose death rate in the U.S. from 1999 to 2023, per 100,000 population.
Profit from the additional features of your individual account
Currently, you are using a shared account. To use individual functions (e.g., mark statistics as favourites, set
statistic alerts) please log in with your personal account.
If you are an admin, please authenticate by logging in again.
Learn more about how ÌÇÐÄÆƽâ°æ can support your business.
CDC. (December 22, 2024). Age-adjusted rate of drug overdose deaths in the U.S. from 1999 to 2023 (per 100,000 population) [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 27, 2026, from /statistics/1092465/drug-overdose-age-adjusted-death-rates-in-us/
CDC. "Age-adjusted rate of drug overdose deaths in the U.S. from 1999 to 2023 (per 100,000 population)." Chart. December 22, 2024. ÌÇÐÄÆƽâ°æ. Accessed July 27, 2026. /statistics/1092465/drug-overdose-age-adjusted-death-rates-in-us/
CDC. (2024). Age-adjusted rate of drug overdose deaths in the U.S. from 1999 to 2023 (per 100,000 population). ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 27, 2026. /statistics/1092465/drug-overdose-age-adjusted-death-rates-in-us/
CDC. "Age-adjusted Rate of Drug Overdose Deaths in The U.S. from 1999 to 2023 (per 100,000 Population)." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 22 Dec 2024, /statistics/1092465/drug-overdose-age-adjusted-death-rates-in-us/
CDC, Age-adjusted rate of drug overdose deaths in the U.S. from 1999 to 2023 (per 100,000 population) ÌÇÐÄÆƽâ°æ, /statistics/1092465/drug-overdose-age-adjusted-death-rates-in-us/ (last visited July 27, 2026)
Age-adjusted rate of drug overdose deaths in the U.S. from 1999 to 2023 (per 100,000 population) [Graph], CDC, December 22, 2024. [Online]. Available: /statistics/1092465/drug-overdose-age-adjusted-death-rates-in-us/
