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This statistic displays the most common adverse events from rotavirus vaccines by strain as of 2011. During this time, six percent of those immunized with live reassortant human-bovine rotavirus reported diarrhea as adverse event. Rotavirus is a highly contagious viral disease and is the most common cause of severe diarrhea in infants and young children. It causes about 1 billion U.S. dollars in the United States alone every year. Vaccination for rotavirus is often made from a single strain or from combining five human-bovine viruses