
Matej Mikulic
Research expert covering health, pharma & medtech
Japan remains one of the world's largest pharmaceutical markets, yet its relative global position has been steadily contracting. Japan's share of global pharmaceutical revenue has declined while North America's has grown, highlighting a structural shift in where the industry's value is being created. Domestically, demand continues to expand:Â the prescription drug market reached 11.5 trillion Japanese yen (approximately 76 billion U.S. dollars) in 2024, its highest value on record, and total pharmaceutical production value exceeded 10.25 trillion yen (~68 bn USD). Yet this trajectory, driven by one of the world's oldest populations, does not translate into a growing share of the global innovation economy, thus pointing to a gap between Japan's healthcare needs and its influence on the industry's international development.

Detailed statistics
Production value of pharmaceutical drugs Japan 2014-2024

Detailed statistics
Share of drug production value Japan 2023, by category

Detailed statistics
Value of imported pharmaceutical drugs to Japan 2014-2023

Global pharmaceutical market - revenue distribution 2010-2025, by region
Distribution of global pharmaceutical market revenue from 2010 to 2025, by region

Prescription drug market size Japan 2003-2024
Sales value of the prescription drug market in Japan from 2003 to 2024 (in trillion Japanese yen)

Number of medical drug manufacturing plants Japan 2023, by production value
Number of medical drug manufacturing plants in Japan in 2023, by production value

Production value of pharmaceutical drugs Japan 2014-2024
Production value of pharmaceutical drugs in Japan from 2014 to 2024 (in trillion Japanese yen)

Major pharmaceutical companies in prescription drug sales Japan 2024, by distributor
Leading pharmaceutical companies in sales of prescription drugs in Japan in 2024, by distributor level (in billion Japanese yen)

Total asset of major companies in pharmaceutical industry Japan 2024
Total assets of leading pharmaceutical companies in Japan as of March 2024 (in billion Japanese yen)

Takeda Pharmaceutical's revenue FY 2015-2024
Revenue of Takeda Pharmaceutical from fiscal year 2015 to 2024 (in trillion Japanese yen)

Daiichi Sankyo Company, Limited revenue 2020-2024
Revenue of Daiichi Sankyo Company, Limited from 2020 to 2024 (in billion Japanese yen)

Chugai Pharmaceutical Co., Ltd. revenue 2021-2025
Revenue of Chugai Pharmaceutical Co., Ltd. from 2021 to 2025 (in billion Japanese yen)

Otsuka Holdings Co., Ltd. revenue 2021-2025
Revenue of Otsuka Holdings Co., Ltd. from 2021 to 2025 (in trillion Japanese yen)

Astellas Pharma Inc. revenue 2020-2024
Revenue of Astellas Pharma Inc. from 2020 to 2024 (in trillion Japanese yen)

Share of the volume of generics in the prescription drug market Japan 2013-2024
Share of the volume of generics in the prescription drug market in Japan from 2013 to 2024

Share of prescription and OTC drug in wholesale Japan FY 2013-2022
Distribution of ethical pharmaceuticals and over-the-counter (OTC) medication wholesales in Japan from fiscal year 2013 to 2022

Share of prescription drug sales Japan FY 2014-2023, by channel
Distribution of prescription drug sales in Japan from fiscal year 2014 to 2023, by channel

Sales value of major prescription drugs Japan 2024
Annual sales value of the leading prescription drugs in Japan in 2024 (in billion Japanese yen)

Share of drug production value Japan 2023, by category
Distribution of the pharmaceutical drug production value in Japan in 2023, by main therapeutic category of drugs

Share of drug production value Japan 2023, by drug form
Distribution of the pharmaceutical drug production value in Japan in 2023, by drug form

Production value of prescription drugs Japan 2014-2023
Production value of prescription drugs in Japan from 2014 to 2023 (in trillion Japanese yen)

R&D spending of pharmaceutical companies Japan FY 2015-2023
Research and development (R&D) expenditures in the pharmaceutical manufacturing companies in Japan from fiscal year 2015 to 2023 (in billion Japanese yen)

R&D expenditure of leading pharmaceutical manufacturers Japan FY 2023
Research and development (R&D) expenditures of leading pharmaceutical manufacturers in Japan in fiscal year 2023 (in million Japanese yen)

R&D spending of pharmaceutical companies in relation to sales Japan FY 2015-2023
Research and development (R&D) expenditure as a share of sales of pharmaceutical manufacturing companies in Japan from fiscal year 2015 to 2023

Number of new drugs approved by PMDA Japan FY 2014-2023
Number of new drugs approved by the Pharmaceuticals and Medical Devices Agency (PMDA) in Japan from fiscal year 2014 to 2023

Number of prescription drugs approved by PMDA Japan FY 2015-2023, by type
Number of prescription drugs approved by the Pharmaceuticals and Medical Devices Agency (PMDA) in Japan from fiscal year 2015 to 2023, by type

Number of pharmaceutical products approved by PMDA Japan FY 2023, by type
Number of pharmaceutical products approved by the Pharmaceuticals and Medical Devices Agency (PMDA) in Japan in fiscal year 2023, by type

Companies with the highest number of pharmaceutical patent applications Japan 2023
Business enterprises which filed the highest number of pharmaceutical patent applications at the Japan Patent Office in 2023

Wholesale value of pharmaceuticals Japan FY 2023, by category
Wholesale value of pharmaceuticals in Japan in fiscal year 2023, by category (in billion Japanese yen)

Pharma sales value of manufacturers and sellers Japan FY 2023, by product type
Sales value of medicine of pharmaceutical manufacturers and sellers in Japan in fiscal year 2023, by product type (in billion Japanese yen)

Pharma sales value of manufacturers and sellers Japan FY 2023, by sales region
Sales value of medicine of pharmaceutical manufacturers and sellers from Japan in fiscal year 2023, by sales region (in billion Japanese yen)

Value of imported pharmaceutical drugs to Japan 2014-2023
Value of pharmaceutical drug imports to Japan from 2014 to 2023 (in trillion Japanese yen)

Value of exported pharmaceutical drugs from Japan 2014-2023
Value of pharmaceutical drug exports from Japan 2014 to 2023 (in billion Japanese yen)

Age distribution of the population Japan 1950-2070
Distribution of the population in Japan in 1950 and 2024 with a forecast for 2070, by age group

Revenue in the pharmaceuticals market in Japan 2016-2030
Revenue in the pharmaceuticals market in Japan from 2016 to 2030 (in billion U.S. dollars)

Share of drug production value Japan 2014-2023, by type
Distribution of the pharmaceutical drug production value in Japan from 2014 to 2023, by type

Median approval time of new drugs Japan 2004-2024, by type
Median approval time of new drugs in Japan from 2004 to 2024, by product type (in months)

Ad expenses of the pharmaceuticals industry Japan 2015-2024
Advertising expenditure of the pharmaceutical and medical industry through traditional media in Japan from 2015 to 2024 (in billion Japanese yen)
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