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Breast cancer incidence rates among women in the United States vary by race and ethnicity. Non-Hispanic white women face the highest risk, with  cases per 100,000 population from 2017 to 2021. In comparison, the incidence rate for breast cancer among Hispanic women during this period was *** per 100,000 population. This stark contrast in incidence rates highlights the importance of understanding racial and ethnic disparities in breast cancer diagnosis and treatment.

Demographic factors influence breast cancer risk

While non-Hispanic white women have the highest incidence rate, other racial and ethnic groups also face substantial risks. Non-Hispanic Black women have the second-highest rate at cases per 100,000, followed by American Indian/Alaska Native women at . These variations underscore the need for targeted prevention and screening efforts. Interestingly, breast cancer incidence rates also differ by state, with Connecticut reporting the highest rate with *** cases per 100,000 population in 2021.

Molecular subtypes and age impact breast cancer incidence

The distribution of breast cancer subtypes varies among racial and ethnic groups, potentially contributing to differences in incidence rates. For white women, the hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) subtype accounts for ** percent of cases, which is generally less aggressive and slower growing. Age also plays a significant role in breast cancer risk, with women aged 60 to 69 accounting for * ductal carcinoma in situ (DCIS) cases and * invasive breast cancer cases in 2024. These factors emphasize the complexity of breast cancer epidemiology and the need for comprehensive research and prevention strategies.