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In the United States, the leading causes of death among women are heart disease and cancer. Heart disease and cancer are similarly the leading causes of death among U.S. men. In 2023, heart disease accounted for **** percent of all deaths among women in the United States, while cancer accounted for **** percent of deaths. COVID-19 was the third leading cause of death among women in 2020 and 2021, and the fourth leading cause in 2022, however, by 2023 it had dropped to ninth place. 

Cancer among women in the U.S.

The most common types of cancer among U.S. women are breast, lung and bronchus, and colon and rectum. In 2025, there were around ** new breast cancer cases among women, compared to ** new cases of lung and bronchus cancer. Although breast cancer is the most common form of cancer among women in the United States, lung and bronchus cancer causes the highest number of cancer deaths. In 2025, around * women were expected to die from lung and bronchus cancer, compared to * from breast cancer.

Breast cancer

Although breast cancer is the second most deadly form of cancer among women, rates of death have decreased over the past few decades. This decrease is possibly due to early detection, progress in therapy, and increasing awareness of risk factors. In 2023, the death rate due to breast cancer was **** per 100,000 population, compared to a rate of **** per 100,000 in the year 1990. The state with the highest rate of deaths due to breast cancer is Oklahoma, while South Dakota had the lowest rates.