In 2024, the rate of reported syphilis cases in the United States was around ** per 100,000. The rate of cases fell significantly in the U.S. during the 1990s, but cases rose again considerably around 2020.
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CDC. (September 24, 2025). Rates of reported syphilis cases in the United States from 1950 to 2024 (per 100,000 population) [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved August 04, 2026, from /statistics/622892/rate-of-syphilis-cases-in-the-united-states/
CDC. "Rates of reported syphilis cases in the United States from 1950 to 2024 (per 100,000 population)." Chart. September 24, 2025. ÌÇÐÄÆÆ½â°æ. Accessed August 04, 2026. /statistics/622892/rate-of-syphilis-cases-in-the-united-states/
CDC. (2025). Rates of reported syphilis cases in the United States from 1950 to 2024 (per 100,000 population). ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: August 04, 2026. /statistics/622892/rate-of-syphilis-cases-in-the-united-states/
CDC. "Rates of Reported Syphilis Cases in The United States from 1950 to 2024 (per 100,000 Population)." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 24 Sep 2025, /statistics/622892/rate-of-syphilis-cases-in-the-united-states/
CDC, Rates of reported syphilis cases in the United States from 1950 to 2024 (per 100,000 population) ÌÇÐÄÆÆ½â°æ, /statistics/622892/rate-of-syphilis-cases-in-the-united-states/ (last visited August 04, 2026)
Rates of reported syphilis cases in the United States from 1950 to 2024 (per 100,000 population) [Graph], CDC, September 24, 2025. [Online]. Available: /statistics/622892/rate-of-syphilis-cases-in-the-united-states/