This statistic depicts the top global pharmaceutical companies based on pharmaceutical revenue in 2022. In that year, Swiss corporation Novartis generated some ** billion U.S. dollars of pharmaceutical revenue. Pfizer, however, held on to the first place, still mostly due to record-breaking COVID-19 vaccine sales.
Top global pharmaceutical companies
The top pharmaceutical companies when based exclusively on prescription drug revenue with pharmaceutical products are Pfizer, AbbVie, and Johnson & Johnson, as of 2022. The companies generated ** billion U.S. dollars, ** billion U.S. dollars, and ** billion U.S. dollars, respectively, in that year. Swiss company Novartis has not maintained its top 3 ranking from previous years. Novartis is a multinational company based in Basel, Switzerland. The company was established in 1996 through the merger of Swiss pharmaceutical companies, Ciba-Geigy and Sandoz Laboratories. One of Novartis' segment consists of over-the-counter drugs such as Excedrin, sold in the United States. This is a drug normally marketed as a headache pain reliever and sold in the form of a tablet or caplet.
From the United Sates, Johnson & Johnson remains one of the largest biotechnology and pharmaceutical companies as of 2022, generating some ** billion U.S. dollars in total pharmaceuticals revenue. Johnson & Johnson’s revenue from the company’s top three drugs accounted for around ** percent of the company’s total pharmaceutical revenues in 2022. In 2022, the U.S. pharma industry spent over ** billion U.S. dollars within the country on pharmaceutical research and development and nearly ** billion U.S. dollars abroad.
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PharmaBoardroom. (June 20, 2023). Leading global pharmaceutical companies based on pharma revenue in 2022 (in billion U.S. dollars) [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 27, 2026, from /statistics/281306/major-global-pharmaceutical-companies-based-on-pharma-revenue/
PharmaBoardroom. "Leading global pharmaceutical companies based on pharma revenue in 2022 (in billion U.S. dollars)." Chart. June 20, 2023. ÌÇÐÄÆÆ½â°æ. Accessed July 27, 2026. /statistics/281306/major-global-pharmaceutical-companies-based-on-pharma-revenue/
PharmaBoardroom. (2023). Leading global pharmaceutical companies based on pharma revenue in 2022 (in billion U.S. dollars). ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 27, 2026. /statistics/281306/major-global-pharmaceutical-companies-based-on-pharma-revenue/
PharmaBoardroom. "Leading Global Pharmaceutical Companies Based on Pharma Revenue in 2022 (in Billion U.S. Dollars)." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 20 Jun 2023, /statistics/281306/major-global-pharmaceutical-companies-based-on-pharma-revenue/
PharmaBoardroom, Leading global pharmaceutical companies based on pharma revenue in 2022 (in billion U.S. dollars) ÌÇÐÄÆÆ½â°æ, /statistics/281306/major-global-pharmaceutical-companies-based-on-pharma-revenue/ (last visited July 27, 2026)
Leading global pharmaceutical companies based on pharma revenue in 2022 (in billion U.S. dollars) [Graph], PharmaBoardroom, June 20, 2023. [Online]. Available: /statistics/281306/major-global-pharmaceutical-companies-based-on-pharma-revenue/