Maternal syphilis refers to a syphilis infection detected at the beginning of pregnancy or diagnosed during pregnancy, with or without evidence of treatment. Treatment documentation during the current pregnancy suffices if a clear diagnosis is absent in the existing medical records.
Maternal syphilis rate: Number of live births to women with syphilis per 100,000 live births. Although this analysis describes the prevalence of maternal syphilis, the unit of analysis is births.
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Maternal syphilis rates during pregnancy in the U.S. from 2016 to 2022
In the United States, the overall rate of syphilis among mothers delivering babies more than tripled from 2016 to 2022, increasing from 87.2 to 280.4 cases per 100,000 births. This statistic depicts the rate of maternal syphilis during pregnancy in the United States from 2016 to 2022, per 100,000 births.
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NCHS, & CDC. (February 14, 2024). Maternal syphilis rates during pregnancy in the United States from 2016 to 2022 (per 100,000 births) [Graph]. In ÌÇÐÄÆÆ½â°æ. Retrieved July 24, 2026, from /statistics/1452048/maternal-syphilis-rates-during-pregnancy-us/
NCHS, und CDC. "Maternal syphilis rates during pregnancy in the United States from 2016 to 2022 (per 100,000 births)." Chart. February 14, 2024. ÌÇÐÄÆÆ½â°æ. Accessed July 24, 2026. /statistics/1452048/maternal-syphilis-rates-during-pregnancy-us/
NCHS, CDC. (2024). Maternal syphilis rates during pregnancy in the United States from 2016 to 2022 (per 100,000 births). ÌÇÐÄÆÆ½â°æ. ÌÇÐÄÆÆ½â°æ Inc.. Accessed: July 24, 2026. /statistics/1452048/maternal-syphilis-rates-during-pregnancy-us/
NCHS, and CDC. "Maternal Syphilis Rates during Pregnancy in The United States from 2016 to 2022 (per 100,000 Births)." ÌÇÐÄÆÆ½â°æ, ÌÇÐÄÆÆ½â°æ Inc., 14 Feb 2024, /statistics/1452048/maternal-syphilis-rates-during-pregnancy-us/
NCHS & CDC, Maternal syphilis rates during pregnancy in the United States from 2016 to 2022 (per 100,000 births) ÌÇÐÄÆÆ½â°æ, /statistics/1452048/maternal-syphilis-rates-during-pregnancy-us/ (last visited July 24, 2026)
Maternal syphilis rates during pregnancy in the United States from 2016 to 2022 (per 100,000 births) [Graph], NCHS, & CDC, February 14, 2024. [Online]. Available: /statistics/1452048/maternal-syphilis-rates-during-pregnancy-us/