Estimates are age-adjusted using the projected 2000 U.S. Census Bureau population as the standard population and five age groups (18–24, 25–44, 45–64, 65–84,
and ≥85 years.
* Pain reported on most days or every day during the previous 3 months.
** Chronic pain that limits life or work activities on most days or every day during the previous 3 months.
Citation formats
Prevalence of chronic pain among U.S. adults in 2021, by region
In 2021, it was estimated that around 21 percent of adults in the Midwest of the United States suffered from chronic pain, compared to around 17 percent of adults in the Northeast. This statistic shows the percentage of adults in the U.S. with chronic pain in 2021, by region.
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CDC, & MMWR. (April 14, 2023). Percentage of adults in the U.S. with chronic pain in 2021, by region [Graph]. In ÌÇÐÄÆƽâ°æ. Retrieved July 30, 2026, from /statistics/1383869/chronic-pain-adults-prevalence-by-region-us/
CDC, und MMWR. "Percentage of adults in the U.S. with chronic pain in 2021, by region." Chart. April 14, 2023. ÌÇÐÄÆƽâ°æ. Accessed July 30, 2026. /statistics/1383869/chronic-pain-adults-prevalence-by-region-us/
CDC, MMWR. (2023). Percentage of adults in the U.S. with chronic pain in 2021, by region. ÌÇÐÄÆƽâ°æ. ÌÇÐÄÆƽâ°æ Inc.. Accessed: July 30, 2026. /statistics/1383869/chronic-pain-adults-prevalence-by-region-us/
CDC, and MMWR. "Percentage of Adults in The U.S. with Chronic Pain in 2021, by Region." ÌÇÐÄÆƽâ°æ, ÌÇÐÄÆƽâ°æ Inc., 14 Apr 2023, /statistics/1383869/chronic-pain-adults-prevalence-by-region-us/
CDC & MMWR, Percentage of adults in the U.S. with chronic pain in 2021, by region ÌÇÐÄÆƽâ°æ, /statistics/1383869/chronic-pain-adults-prevalence-by-region-us/ (last visited July 30, 2026)
Percentage of adults in the U.S. with chronic pain in 2021, by region [Graph], CDC, & MMWR, April 14, 2023. [Online]. Available: /statistics/1383869/chronic-pain-adults-prevalence-by-region-us/
