
Matej Mikulic
Research expert covering health, pharma & medtech
Among global top pharmaceutical players, it is quite rare that a company focuses more or less on just one medical condition. Novo Nordisk is one of these rare companies, putting almost all its weight on the development of treatments and therapies for diabetes. The company is headquartered in a suburb of Copenhagen, Denmark. The Scandinavian country is a pharmaceutical stronghold, especially in relation to its size. Novo Nordisk is probably the best-known Danish company worldwide and the country’s second largest in terms of revenue, just behind transportation and logistics giant Maersk.
In 2023, Novo Nordisk celebrated its 100-year anniversary. From the very beginning in 1923, the then-called Nordisk Insulinlaboratorium focused on the treatment of diabetes and the production of insulin. Back in 2024, Novo Nordisk was ranked second among the top global pharma and biotech companies based on market capitalization, but in the meantime it lost ground and was ranked 10th as of early 2026. It is the world’s largest company for diabetes treatments, with more than two thirds of its around 49-billion-dollar global sales being generated through the company’s diabetes care business. Important competitors in this market are companies like Eli Lilly, Boehringer Ingelheim, and Sanofi. Novo Nordisk’s top diabetes drug is Ozempic, a GLP-1 receptor agonist that increases insulin secretion. Ozempic generated around 20 billion U.S. dollars of revenue in 2025. But while officially a diabetes treatment, Ozempic generates a large share of its revenues by being used off-label as a weight loss drug.Â
Semaglutide was the major driver for Novo Nordisk’s growth over the last years. Both Wegovy and Ozempic (and Rybelsus) have the same active ingredient, semaglutide — only the dosage is different. Within the years 2022-2023, Wegovy's quarterly sales increased eightfold, while in 2024 it still doubled. Similar to Ozempic, growth was only moderate in 2025. The major reason for that is the rise of Eli Lilly, top challenger in the weight loss market. Its metabolic products Mounjaro and Zepbound show higher effectiveness than Novo Nordisk's counterparts. Analysts also emphasize Eli Lilly's more potent pipeline which is mirrored in the company's much higher market capitalization compared to Novo Nordisk.Â
Overweight and obesity are huge issues in developed countries, causing many health risks like heart diseases and diabetes. The number of people with diabetes and overweight around the world is projected to increase dramatically over the next decades. Thus, weight loss drugs are seen in a much broader picture than just losing weight, suggesting they might become a cornerstone in preventive healthcare around the globe. Within a decade, the obesity market could reach 150 billion U.S. dollar globally. It's no wonder that several other pharmaceutical companies started to enter the race for market shares. So far, Novo Nordisk is still holding its position as incumbent and more than half of the weight loss market.Â

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Major 50 pharmaceutical companies - Rx sales and R&D spending 2024

Detailed statistics
Leading 10 biotech and pharmaceutical companies based on market cap 2026

Pharmaceutical market size worldwide 2001-2029
Market size of the worldwide pharmaceutical industry from 2001 to 2024, with estimates for 2029 (in billion U.S. dollars)

Major 50 pharmaceutical companies - Rx sales and R&D spending 2024
Leading 50 global pharmaceutical companies by prescription sales and R&D spending in 2024 (in billion U.S. dollars)

Leading 10 biotech and pharmaceutical companies based on market cap 2026
Leading 10 biotech and pharmaceutical companies worldwide as of February 2026, by market capitalization (in billion U.S. dollars)

Leading global biotech and pharmaceutical companies 2026, by net income
Leading global biotech and pharmaceutical companies in 2026, by net income (in billion U.S. dollars)

Sales forecast of top-selling drugs worldwide 2030
Projected best-selling pharmaceutical drugs worldwide in 2030 (in billion U.S. dollars)

Ad spending of selected diabetes/weight loss drugs in the U.S. 2025
Advertising spending of selected diabetes and weight loss drugs in the United States in 2025 (in million U.S. dollars)

Novo Nordisk net sales 2009-2025
Net sales of Novo Nordisk from 2009 to 2025 (in million DKK)

Novo Nordisk net profit 2009-2025
Net profit of Novo Nordisk from 2009 to 2025 (in million DKK)

R&D costs of Novo Nordisk 2018-2025
Novo Nordisk's research and development costs from 2018 to 2025 (in million kroner)

Novo Nordisk total assets 2021-2025
Total assets of Novo Nordisk from 2021 to 2025 (in billion Danish kroner)

Novo Nordisk sales share by therapy area 2021-2025
Novo Nordisk's sales distribution by therapeutic area from 2021 to 2025

Novo Nordisk sales by therapy area 2022-2025
Novo Nordisk's sales by therapeutic area from 2022 to 2025 (in million DKK)

Novo Nordisk sales in diabetes subsegments 2025
Novo Nordisk's diabetes care sales in 2025, by subsegment (in million DKK)

Novo Nordisk sales share by region 2025
Novo Nordisk's sales distribution in 2025, by world region

Eli Lilly's total revenue by segment 2022-2025
Revenue of Eli Lilly and Company from 2022 to 2025, by segment (in million U.S. dollars)

Sanofi pharmaceutical segment revenues by product group 2025
Revenue of Sanofi's pharmaceutical segment by product group in 2025 (in million euros)

AstraZeneca revenue by therapeutic area 2022-2025
Revenue of AstraZeneca from 2022 to 2025, by therapy area (in million U.S. dollars)

Boehringer Ingelheim's distribution of revenue 2016-2025, by business
Distribution of Boehringer Ingelheim's revenue from 2016 to 2025, by business area

Revenue share of Roche's Pharmaceuticals division by therapy area 2013-2025
Revenue distribution of Roche's Pharmaceuticals division from 2013 to 2025, by therapeutic area

Anti-obesity drugs market size worldwide 2025-2040
Anti-obesity drugs market size worldwide from 2025 to 2040 (in billion U.S. dollars)

Economic impact of high BMI as share of GDP worldwide in 2020 and forecasts to 2035
Global economic impact of overweight and obesity as proportion of total global GDP in 2020 and forecasts to 2035

Market share of leading weight loss drugs worldwide Q2 2024-Q1 2025
Market share of leading weight loss drugs worldwide from the second quarter of 2024 to the first quarter of 2025

Ozempic net sales of Novo Nordisk 2020-2025
Ozempic net sales of Novo Nordisk from 2020 to 2025 (in million DKK)

Wegovy sales of Novo Nordisk Q1 2022-Q1 2026
Quarterly sales of Novo Nordisk's Wegovy from first quarter 2022 to first quarter 2026 (in million DKK)
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