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Vaccine-preventable diseases in the U.S.

Statistics report about vaccination-preventable diseases in the United States

This report presents key facts and figures about vaccine-preventable diseases in the United States. It contains figures on the vaccine coverage against, and incidence of, select diseases globally, with a specific focus on the impact of these diseases within the United States.

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Table of contents

Overview

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  • Basic Statistic Number of vaccine-preventable disease cases worldwide 1980-2024, by disease
  • Premium Statistic Global vaccination coverage in 2022, by vaccine type
  • Basic Statistic Vaccination coverage Americas vs globally 2022, by vaccine type
  • Premium Statistic Vaccination coverage among U.S. adolescents as of 2024, by age
  • Basic Statistic Cases of vaccine-preventable diseases in the U.S. from 1980 to 2022, by disease
  • Basic Statistic Cases of infectious diseases before and after the use of vaccines U.S. 2022
  • Premium Statistic Major causes of death in the U.S. for 1900 and 2024

Global disease incidence

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  • Premium Statistic Incidence of tuberculosis worldwide by region 2023
  • Basic Statistic Positive influenza cases per week worldwide in 2021, by type
  • Premium Statistic Number of measles cases worldwide from 1980 to 2024, by region
  • Basic Statistic Number of mumps cases worldwide from 1999 to 2024, by region
  • Basic Statistic Number of rubella cases worldwide from 1999 to 2023, by region
  • Premium Statistic Number of cases of diphtheria worldwide from 1980 to 2024, by region
  • Basic Statistic Number of tetanus cases worldwide from 1980 to 2024, by region
  • Premium Statistic Number of pertussis (whooping cough) cases worldwide from 1980 to 2024, by region
  • Basic Statistic Number of polio cases worldwide from 1980 to 2024, by region
  • Basic Statistic Number of smallpox cases worldwide 1920-1980
  • Basic Statistic Number of countries where smallpox was eradicated in nature 1872-1977

Tuberculosis (BCG Immunization)

5
  • Premium Statistic Number of new cases of tuberculosis in the U.S. 1953-2023
  • Premium Statistic Rate of new cases of tuberculosis in the U.S. 1953-2024
  • Premium Statistic New cases of tuberculosis in the U.S. 2023, by state
  • Basic Statistic New cases of tuberculosis in the U.S. from 2016 to 2023, by national origin
  • Basic Statistic Death rate for tuberculosis in the U.S. 1960-2022

Influenza (HiB Immunization)

8
  • Premium Statistic Flu vaccine coverage in the U.S. 2014-2025, by age
  • Premium Statistic Percentage of U.S. older people who received influenza vaccination 2010-2025
  • Basic Statistic Number of influenza cases in the United States from 2011-2025
  • Premium Statistic Number of influenza hospitalizations in the United States from 2011-2024
  • Basic Statistic Number of influenza deaths in the United States from 2010-2025
  • Basic Statistic Deaths by influenza and pneumonia in the U.S. 1950-2023
  • Basic Statistic Number of influenza vaccinations needed to prevent one hospitalization U.S. 2018-2019
  • Premium Statistic Number of deaths prevented by influenza vaccinations U.S. 2023-2024, by age

Measles Mumps and Rubella (MMR Immunization)

7
  • Basic Statistic MMR vaccination rate among U.S. children aged 19-35 months 1995-2017
  • Basic Statistic New cases of measles in the U.S. 1985-2026
  • Basic Statistic Rate of new cases of measles in the U.S. 1919-2026
  • Basic Statistic Number of measles cases in the U.S. in 2021, by region
  • Basic Statistic New cases of mumps in the U.S. 1970-2019
  • Basic Statistic Number of mumps cases in the U.S. in 2021, by region
  • Premium Statistic Number of rubella cases in the U.S. from 1998 to 2023

Diphtheria Tetanus and Pertussis (DTP3 Immunization)

8
  • Premium Statistic DTP3 immunization coverage in the U.S. from 2000 to 2023
  • Premium Statistic New cases of diphtheria in the U.S. 1950-2019
  • Premium Statistic Number of diphtheria deaths in the U.S. from 1990 to 2019
  • Basic Statistic Number of U.S. tetanus cases from 1980 to 2023
  • Basic Statistic Number of tetanus deaths in the U.S. from 1990 to 2019
  • Basic Statistic Cases of pertussis in the U.S. 1950-2019
  • Basic Statistic Rate of pertussis among U.S. population by state 2018
  • Basic Statistic Number of whooping cough deaths in the U.S. from 1990 to 2019

Hepatitis A and B

7
  • Premium Statistic Hepatitis B immunization coverage in the U.S. among one-year-olds, 2000-2023
  • Premium Statistic Rate of hepatitis B infections in the U.S. in 2023, by state
  • Premium Statistic Rate of hepatitis B-related deaths in the U.S. in 2023, by age
  • Basic Statistic Hepatitis A infection rate in the U.S. in 2023, by state
  • Basic Statistic Rate of hepatitis A-related deaths in the U.S. in 2023, by age
  • Premium Statistic New cases of hepatitis A and B 1970-2023
  • Premium Statistic Rate of viral hepatitis-related deaths in the U.S. from 2019-2023, by type

Human Papilloma Virus (HPV Immunization)

7
  • Basic Statistic HPV vaccine coverage among U.S. adolescents as of 2024, by age
  • Basic Statistic Share of U.S. college students vaccinated against HPV as of fall 2025, by gender
  • Basic Statistic U.S. adults who received the recommended doses of the HPV vaccine 2013-2018 by gender
  • Premium Statistic Number of cancer cases that were caused by HPV in the U.S. 2017-2021, by site
  • Premium Statistic Percentage of select cancers that were caused by HPV in the U.S. 2017-2021, by gender
  • Premium Statistic Percentage of select cancers that were caused by HPV in the U.S. 2017-2021, by site
  • Basic Statistic U.S. rate of new alcohol-associated cancers in 2022, by state
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