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Clinical trials

Statistics report about clinical research

This report presents key facts and figures about clinical trials worldwide, with a focus on the United States. Clinical trials are also known as Phase I to IV within the research, development, and approval process for new drugs, medical devices, or procedures. This report gives you an overview about health R&D in general, number of clinical studies, success rates, costs, etc.

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Table of contents

R&D overview

7
  • Premium Statistic Total global pharmaceutical R&D spending 2016-2030
  • Premium Statistic Industry sectors - expenditure on research and development 2024
  • Premium Statistic Major pharmaceutical R&D projects 2026, by net present value
  • Basic Statistic Research and development expenditure: U.S. pharmaceutical industry 1995-2024
  • Premium Statistic Research and development in European pharmaceutical industry by country 2024
  • Premium Statistic Clinical trials market size worldwide 2024-2033
  • Premium Statistic Total clinical research funding by National Institutes for Health 2013-2024

Top R&D companies

3
  • Basic Statistic Leading 50 global pharmaceutical and biotech companies 2024, by R&D intensity
  • Basic Statistic Major pharmaceutical companies in R&D spending growth in 2024
  • Premium Statistic Leading global contract research organizations 2025, based on revenue

Clinical studies

7
  • Basic Statistic Increase in clinical trials' complexity 2001-2015
  • Premium Statistic Clinical trial success rates by therapeutic area 2020
  • Basic Statistic Number of registered clinical studies by location worldwide 2026
  • Basic Statistic Percent of registered clinical studies worldwide by location 2026
  • Premium Statistic Total number of registered clinical studies worldwide 2000-2025
  • Premium Statistic Share of global clinical trials as of March 2025, by intervention type
  • Premium Statistic Share of global clinical trials by primary purpose 2025

Costs and market

4
  • Basic Statistic Pharmaceuticals: cost of drug development in the U.S. since 1975
  • Premium Statistic Per day clinical trial mean direct cost by phase
  • Basic Statistic Total CRO market size worldwide 2015-2024
  • Premium Statistic Global pharma CRO market size 2015-2024, by pre-clinical, clinical and discovery

Countries and regions

5
  • Basic Statistic Share of clinical trials started worldwide 2013-2023, by region
  • Premium Statistic Share of commercial clinical trial starts worldwide 2013-2023, by region
  • Premium Statistic Number of commercial clinical trial starts in top countries 2023 vs 2018
  • Premium Statistic Number of clinical trials APAC 1999-2025, by country
  • Premium Statistic Clinical studies in Latin America 2025, by country

Approvals, launches, setbacks

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  • Premium Statistic Pharmaceutical industry - number of new substances 1998-2025
  • Premium Statistic Number of novel drugs approved annually by CDER 2008-2025
  • Basic Statistic Key measurements of U.S. CDER drug approvals in 2025
  • Premium Statistic Major pharma and biotech drug launches in 2026, by revenue estimates for 2032
  • Basic Statistic Number of unsuccessful Alzheimer’s drugs in development in the U.S. 1998-2017

Increasing impact of AI

5
  • Premium Statistic Leading AI in clinical trials companies by funding worldwide 2023
  • Premium Statistic AI-based clinical trials solutions market worldwide 2030 forecast
  • Premium Statistic Number of clinical trials globally that have included mentions of AI 2014-2024
  • Premium Statistic Number of clinical trials that have included mentions of AI 2014-2024, by country
  • Premium Statistic Global AI-enabled drug discovery and clinical trials market by region 2030
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