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Birth defects in the U.S.

Statistics report about birth defects in the United States

This report presents key facts and figures about birth defects in the United States. According to the Centers for Disease Control and Prevention (CDC), around one in 33 babies born every year in the United States has a birth defect. Birth defects can range from mild to severe and the cause for many of them is still unknown. This report contains information about various birth defects including heart defects, chromosomal defects, face defects, and limb defects.

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Table of contents

Overview

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  • Basic Statistic Rate of select birth defects in the U.S. 2016-2020
  • Basic Statistic Total cost of U.S. hospitalizations with a birth defect–associated discharge, 2019
  • Basic Statistic Mean cost of U.S. hospitalizations with a birth defect–associated discharge, 2019
  • Basic Statistic Mortality rates due to congenital birth defects in the United States 1980-2021

Heart defects

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  • Premium Statistic Incidence of select heart birth defects in the United States as of 2024
  • Premium Statistic Number of annual cases of select heart birth defects in the United States as of 2024
  • Premium Statistic Rate of cardiovascular birth defects in the U.S. from 2016-2020, by race
  • Premium Statistic Rate of ventricular septal defects among U.S. babies from 2016 to 2020, by state
  • Premium Statistic Rate of pulmonary valve atresia/stenosis among U.S. babies, 2016-2020, by state
  • Basic Statistic Average life span for complex congenital heart defects in the U.S. as of 2024
  • Basic Statistic Average annual costs of complex congenital heart defects in the U.S. as of 2024
  • Basic Statistic Lifetime costs of complex congenital heart defects in the U.S. as of 2024
  • Basic Statistic Mean cost of U.S. hospitalizations with a cardiovascular birth defect, 2019

Chromosomal defects

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  • Basic Statistic Incidence of select chromosome birth defects in the United States as of 2024
  • Basic Statistic Number of annual cases of select chromosome birth defects in the U.S. as of 2024
  • Basic Statistic Incidence of Down syndrome in the United States as of 2024, by age
  • Basic Statistic Rate of chromosome (gene) malformation birth defects in the U.S. 2016-2020, by age
  • Basic Statistic Rate of chromosome (gene) malformation birth defects in the U.S. 2016-2020, by race
  • Basic Statistic Rate of Down syndrome among U.S. babies from 2016 to 2020, by state
  • Premium Statistic Mean cost of U.S. hospitalizations with a chromosomal birth defect, 2019

Mouth, face, and eye defects

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  • Basic Statistic Incidence of select mouth/face/eye birth defects in the United States as of 2024
  • Premium Statistic Number of annual cases of select mouth/face/eye birth defects in the U.S. as of 2024
  • Premium Statistic Rate of mouth, face, and eye birth defects in the U.S. from 2016-2020, by race
  • Basic Statistic Rate of cleft lip with or without cleft palate among U.S. babies from 2016 to 2021
  • Basic Statistic Rate of cleft lip with or without cleft palate among U.S. babies, 2016-2021, by sex
  • Basic Statistic Rate of cleft lip with/without cleft palate among U.S. babies 2021, by maternal age
  • Basic Statistic Rate of cleft lip with or without cleft palate among U.S. babies in 2021, by race
  • Basic Statistic Rate of cleft lip with or without cleft palate among U.S. babies in 2021, by BMI
  • Premium Statistic Rate of cleft lip with cleft palate among U.S. babies from 2016 to 2020, by state
  • Premium Statistic Mean cost of U.S. hospitalizations with a mouth/face/eye birth defect, 2019

Muscle and bone defects

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  • Basic Statistic Incidence of select muscle/bone birth defects in the United States as of 2024
  • Premium Statistic Number of annual cases of select muscle/bone birth defects in the U.S. as of 2024
  • Basic Statistic Rate of muscle/bone birth defects in the U.S. from 2016-2020, by race
  • Premium Statistic Rate of limb deficiencies among U.S. babies from 2016 to 2020, by state
  • Basic Statistic Rate of clubfoot among U.S. babies, 2016-2020, by state
  • Basic Statistic Mean cost of U.S. hospitalizations with a muscle/bone birth defect, 2019

Other birth defects

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  • Basic Statistic Incidence of select brain/spine birth defects in the United States as of 2024
  • Basic Statistic Number of annual cases of select brain/spine birth defects in the U.S. as of 2024
  • Basic Statistic Rate of central nervous system birth defects in the U.S. from 2016-2020, by race
  • Premium Statistic Mean cost of U.S. hospitalizations with a brain/spine birth defect, 2019
  • Basic Statistic Incidence of select stomach/intestine birth defects in the United States as of 2024
  • Basic Statistic Number of annual cases of select stomach/intestine birth defects, U.S. 2024
  • Basic Statistic Rate of stomach/intestine birth defects in the U.S. from 2016-2020, by race
  • Basic Statistic Mean cost of U.S. hospitalizations with a stomach/intestine birth defect, 2019
  • Basic Statistic Rate of hypospadias among U.S. babies, 2016-2020, by state
  • Basic Statistic Mean cost of U.S. hospitalizations with a genitourinary birth defect, 2019
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