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In 2025, the ratio of national debt to gross domestic product (GDP) of Sao Tome and Principe stood at 55.69 percent. Between 2001 and 2025, the figure dropped by 362.69 percentage points, though the decline followed an uneven course rather than a steady trajectory. The forecast shows the ratio will steadily decline by 17.38 percentage points from 2025 to 2031.

The general government gross debt consists of all liabilities that require payment or payments of interest and/or principal by the debtor to the creditor at a date or dates in the future. Here it is depicted in relation to the country's GDP, which refers to the total value of goods and services produced during a year.